Amyloid precursor protein (APP) and iron both play pivotal roles in the central nervous system, but whether and how iron influences the processing of endogenous APP in neurons remain unclear. Here, we ...

The birth of new neurons in the adult brain intimates a capacity for restoration even in the face of aging and neurodegeneration. Two papers published in the March 24 issue of the Journal of ...

Thanks to our sponsor Digiarty Sofware, makers of new video processing app VideoProc. VideoProc is a new video processing app for 4K and HD videos made to be an all-in-one app for editing, resizing, ...

The sorting receptor SorLA is thought to triage both amyloidogenic and non-amyloidogenic Aβ precursor protein (APP) processing, but exactly how it manages this feat has been a mystery. In a paper in ...

A new study conducted by researchers at the University of Eastern Finland discovered that the APP A673T genetic variant, which protects against Alzheimer’s disease, alters levels of several proteins ...